New stem cell therapy offers relief for dogs with arthritis

By: Roger Coryell
A large, light-colored dog with floppy ears lies on a stone floor. Its head rests on one paw, with a calm and slightly sad expression. The softly blurred background suggests an indoor or patio setting lit by warm, natural light. This peaceful image commonly depicts dogs with arthritis looking for comfort.

As dogs age, many face the discomfort of osteoarthritis (OA), a degenerative joint disease that significantly impacts their quality of life. This common condition affects more than 10 million dogs in the United States, causing chronic pain and reduced mobility. Traditional treatments often fall short, but a recent study highlights a promising new therapy: adipose-derived stem cell therapy.

Study overview

In a study published in “Veterinary Therapeutics,” researchers conducted a randomized, double-blinded, placebo-controlled trial to investigate the effects of adipose-derived mesenchymal stem cells (AD-MSCs) on dogs with chronic osteoarthritis of the hip. The study involved 21 dogs of various breeds, ages, and sizes, all diagnosed with OA.

The treatment process was innovative. Stem cells were harvested from the dog’s own fat tissue, processed, and then injected into the affected hip joints. This method ensures compatibility and avoids ethical concerns related to stem cell use.

Teddy’s journey: A story of hope

Teddy, a Chow Chow/Husky mix, experienced significant improvement after receiving VetStem Cell Therapy for hip osteoarthritis. Teddy loved to play but developed severe arthritis in his right hip, making it difficult to get up. His veterinarian, Dr. Mitch Luce of Live Oak Veterinary Hospital, discussed treatment options with Teddy’s owners, including hip replacement surgery and VetStem Cell Therapy. They chose VetStem Cell Therapy, hoping for a quicker recovery.

Dr. Luce collected a sample of fat tissue from Teddy’s abdomen during a minimally invasive procedure. The fat was sent to the VetStem laboratory, where technicians extracted and concentrated the stem cells. Two doses were prepared and sent back to Dr. Luce for injection. About 48 hours later, Teddy received an injection of his own stem cells into his arthritic hip and an intravenous injection.

Five months after the procedure, Teddy’s owner reported, “Remarkable recovery!! He runs, jumps, and plays with our other dogs and can get up from a down position easily. He occasionally has a slight limp after intense activity, but that is improving. We are so glad we chose VetStem Cell Therapy for him!”

Promising results for arthritis

The study found that dogs treated with AD-MSCs showed significant improvement in several areas compared to those given a placebo:

  • Lameness: Reduction in lameness at both a walk and trot.
  • Pain management: Less pain during joint manipulation.
  • Range of motion: Improved pain-free range of motion.
  • Overall mobility: Enhanced mobility and a higher willingness to engage in activities like walking, running, and playing.

Three dogs, previously considered for euthanasia due to severe pain and disability, improved dramatically, allowing them to live comfortably.

Traditional treatments for OA in dogs often involve non-steroidal anti-inflammatory drugs (NSAIDs), which provide some relief but do not address the underlying issues and may have side effects. Stem cell therapy offers a regenerative approach, potentially repairing damaged tissues and restoring joint function.

What dog owners should know

If your dog is struggling with osteoarthritis, consider the following about AD-MSC therapy:

  • Consult your vet: Not all dogs are suitable candidates for this treatment. Discuss your dog’s condition and treatment options with your veterinarian.
  • Potential benefits: While results can vary, many dogs experience significant improvements in pain and mobility.
  • Availability: This therapy is becoming more widely available. Seek a veterinary practice experienced in stem cell treatments.

Future outlook for dogs with arthritis

The success of this study opens the door to broader applications of stem cell therapy in veterinary medicine. As research progresses, more effective treatments for various conditions may emerge, offering hope for dogs suffering from chronic ailments.

For now, stem cell therapy represents a promising option for managing osteoarthritis in dogs, potentially transforming how we approach joint health in our pets.

 

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