The 150 miles of Highway 395 between Topaz and Bishop (also known as the Eastern Sierra Scenic Byway) ranks right up there with coastal Highway 1 as California's most scenic drive. You'll have trouble keeping Rover's head inside the window and your eyes on the asphalt as you travel this gorgeous route tracing the eastern edge of the Sierra Nevada.
Pick a side road, almost any side road, and you and your four-legged friend will find yourselves surrounded by rugged canyons, granite peaks, rushing streams and vast displays of aspens, cottonwoods and willows that paint the landscape in yellows, oranges and reds for a few short weeks each autumn.